Michele Ganeless currently serves as CEO of Comic Relief US, a role she took on in 2025 after long serving as a board member. Comic Relief uses the power of comedy to fight childhood poverty — changing the stories that keep it invisible, engaging communities to take action, and resourcing local nonprofits doing the work on the ground. She's best known for her earlier tenure as president of Comedy Central from 2004 to 2016, where she built the network into a cultural powerhouse and it became the leading brand in comedy across all platforms, earning numerous Emmy and Peabody awards.